Advanced SOFA Score Calculator | Sequential Organ Failure Assessment

Advanced SOFA Score Calculator

Calculate the Sequential Organ Failure Assessment (SOFA) score using six organ systems: respiratory, coagulation, liver, cardiovascular, central nervous system, and renal function.

Respiratory

PaO₂ / FiO₂ Ratio (mmHg) Respiratory Support No respiratory support Yes — respiratory support

Coagulation

Platelet Count (×10³/µL)

Liver

Total Bilirubin (mg/dL)

Cardiovascular

Cardiovascular Status MAP ≥ 70 mmHg MAP < 70 mmHg Dobutamine — any dose Dopamine ≤ 5 µg/kg/min Dopamine > 5 to 15 µg/kg/min Epinephrine ≤ 0.1 µg/kg/min Norepinephrine ≤ 0.1 µg/kg/min Dopamine > 15 µg/kg/min Epinephrine > 0.1 µg/kg/min Norepinephrine > 0.1 µg/kg/min

Catecholamine doses should generally reflect treatment for at least 1 hour when applying the standard SOFA criteria.

Central Nervous System

Glasgow Coma Scale (GCS)

Renal

Serum Creatinine (mg/dL) Urine Output (mL/day)

For renal scoring, severe low urine output can determine the score even when creatinine is lower.

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SOFA Result

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Organ System Breakdown

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SOFA Trend Tracking

Add sequential SOFA measurements to monitor whether the score is increasing, decreasing, or remaining stable over time.

Trend Date / Time Add SOFA Reading

Date / Time	Total SOFA	Respiratory	Coagulation	Liver	Cardiovascular	CNS	Renal

Trend Interpretation

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SOFA Scoring Criteria

Organ System	0 Points	1 Point	2 Points	3 Points	4 Points
Respiratory PaO₂/FiO₂	≥400	<400	<300	<200 + respiratory support	<100 + respiratory support
Coagulation Platelets ×10³/µL	≥150	<150	<100	<50	<20
Liver Bilirubin mg/dL	<1.2	1.2–1.9	2.0–5.9	6.0–11.9	≥12.0
Cardiovascular	MAP ≥70	MAP <70	Dopamine ≤5 or dobutamine any dose	Dopamine >5–15 or epinephrine/norepinephrine ≤0.1	Dopamine >15 or epinephrine/norepinephrine >0.1
CNS GCS	15	13–14	10–12	6–9	<6
Renal Creatinine / urine output	<1.2	1.2–1.9	2.0–3.4	3.5–4.9 or urine <500 mL/day	≥5.0 or urine <200 mL/day

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About the SOFA Score

The Sequential Organ Failure Assessment (SOFA) score evaluates dysfunction across six organ systems: respiratory, coagulation, liver, cardiovascular, central nervous system, and renal function. Each system receives 0 to 4 points, producing a total score from 0 to 24.

The respiratory component uses the PaO₂/FiO₂ ratio. Lower ratios indicate greater respiratory dysfunction, with the most severe categories requiring respiratory support.

The coagulation component is based on platelet count. Lower platelet counts receive progressively higher SOFA points.

The liver component uses total bilirubin. Higher bilirubin concentrations correspond to higher liver SOFA scores.

The cardiovascular component considers mean arterial pressure and the use and dose of vasoactive medications such as dopamine, epinephrine, norepinephrine, and dobutamine.

The central nervous system component uses the Glasgow Coma Scale. A lower GCS corresponds to a higher SOFA component score.

The renal component uses serum creatinine and urine output. Severe oliguria can result in a high renal SOFA score even when the creatinine concentration alone would suggest a lower score.

SOFA Score Severity

The SOFA score ranges from 0 to 24. A higher score indicates greater overall organ dysfunction. The score is intended for clinical assessment and serial monitoring rather than as a standalone diagnosis.

SOFA Trend Tracking

Serial SOFA measurements can help show whether organ dysfunction is improving, worsening, or remaining stable. A rising score indicates increasing total organ dysfunction, while a falling score may indicate improvement. Individual component scores should also be reviewed because the total score can remain unchanged even when dysfunction shifts between organ systems.

Important Clinical Note

This calculator is for clinical education and decision support. It does not replace bedside assessment, physician judgment, laboratory interpretation, or institutional protocols. SOFA should be interpreted in the context of the patient's complete clinical condition.